New Zealand Herald | Jury told of conflicting theories on girl's death Courtnews.co.nz By David Clarkson. Opening addresses in Gwaze murder trial. The Crown says Charlene Makaza died from a sexual assault by her uncle, George Evans Gwaze, but his defence says she succumbed to an overwhelming infection arising from the HIV the 10-year-old ... U ncle on trial for murder of niece |
Monday, April 30, 2012
Jury told of conflicting theories on girl's death - Courtnews.co.nz
caloloary.blogspot.com
Saturday, April 28, 2012
Mosaic's earnings down 90 percent in 3Q - Minneapolis / St. Paul Business Journal:
qalymeled.wordpress.com
The Plymouth-based fertilizer makerd posted net incomeof $58.8 million, or 13 cents per for the quarter ended Feb. 28. That compares to earnings of $520.8 million, or $1.17 per share, in the comparable period last Revenue came inat $1.38 billion for the down 36 percent from $2.15 billionb a year ago. “Despitwe the turmoil in commodity markets, we remain confideny that long-term agricultural fundamentals are Mosaic President and CEO Jim Prokopank o said ina statement.
“This is a self-correctingh cycle because demand for crop nutriente can only be deferred for so Large crops are still required to securwthe world’s food supply and crop nutriente will play an essential role in achieving that objective.” Mosaixc (NYSE: MOS) makes phosphates and potash fertilizere and feed ingredients for the agricultural
The Plymouth-based fertilizer makerd posted net incomeof $58.8 million, or 13 cents per for the quarter ended Feb. 28. That compares to earnings of $520.8 million, or $1.17 per share, in the comparable period last Revenue came inat $1.38 billion for the down 36 percent from $2.15 billionb a year ago. “Despitwe the turmoil in commodity markets, we remain confideny that long-term agricultural fundamentals are Mosaic President and CEO Jim Prokopank o said ina statement.
“This is a self-correctingh cycle because demand for crop nutriente can only be deferred for so Large crops are still required to securwthe world’s food supply and crop nutriente will play an essential role in achieving that objective.” Mosaixc (NYSE: MOS) makes phosphates and potash fertilizere and feed ingredients for the agricultural
Thursday, April 26, 2012
Cox Newspapers, Inc. Company Profile | Company Information
aleshnikovenil.blogspot.com
Cox Enterprises was founded in 1898 by formerf school teacher and reporterJames M. Cox, whos ambition was to own a newspaper. To realize his he borrowed $26,000 from friends and family and purchased the Dayto nEvening (now Daily) News. In the early years of the Mr. Cox became Ohio's firstg three-term governor and the 1920 Democratic candidate for presidenft of theUnited States. Franklin D. Rooseveltg was his running mate. After losing the election to Warren Harding, Gov. Cox focused his attention on his growinbgmedia business. He established the Miamo (OH) Valley's first radio WHIO, in 1934, just as the mediumn began to gain popularity.
And beford the explosion of television, Cox started WSB-TV in Atlanta, the south'sw first television station in 1948. That same he launched the south's first FM radi o station, WSB-FM. Throughout our first century, Cox Enterprises has builgt its foundationon innovation, service, leadership, quality and growth. Share some of the highlights of our first 100 Since thatinitial investment, privately held Cox Inc., has become one of the nation'sw largest media companies. Headquartered in Atlanta, Cox Enterprisews has continued to be on the forefront of mediaqand technology, branching out into broadcasting, cable television, wholesale auto auctions and interactive media.
Each operatiom company is a unique enterprise, but together we are one solix corporation with a long list ofenviable achievements...
Cox Enterprises was founded in 1898 by formerf school teacher and reporterJames M. Cox, whos ambition was to own a newspaper. To realize his he borrowed $26,000 from friends and family and purchased the Dayto nEvening (now Daily) News. In the early years of the Mr. Cox became Ohio's firstg three-term governor and the 1920 Democratic candidate for presidenft of theUnited States. Franklin D. Rooseveltg was his running mate. After losing the election to Warren Harding, Gov. Cox focused his attention on his growinbgmedia business. He established the Miamo (OH) Valley's first radio WHIO, in 1934, just as the mediumn began to gain popularity.
And beford the explosion of television, Cox started WSB-TV in Atlanta, the south'sw first television station in 1948. That same he launched the south's first FM radi o station, WSB-FM. Throughout our first century, Cox Enterprises has builgt its foundationon innovation, service, leadership, quality and growth. Share some of the highlights of our first 100 Since thatinitial investment, privately held Cox Inc., has become one of the nation'sw largest media companies. Headquartered in Atlanta, Cox Enterprisews has continued to be on the forefront of mediaqand technology, branching out into broadcasting, cable television, wholesale auto auctions and interactive media.
Each operatiom company is a unique enterprise, but together we are one solix corporation with a long list ofenviable achievements...
Tuesday, April 24, 2012
Quiz: Romney Endorsement or Romney Criticism? - Vanity Fair
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Vanity Fair | Quiz: Romney Endorsement or Romney Criticism? Vanity Fair See if you can tell whether each of the following statements about Romney was said in the context of an endorsement or a criticism? 1. Endorsement or criticism?: รข€œIf things had worked out I would have been very happy and honored to support Newt, ... Mitt Romney Defle cts 'Silver Spoon' Criticism, Tells Voters His Grandfather ... Despite Past Criticism, Rudy Giuliani Backs Mitt Romney Romney Vetting Running Mates Stumps With Florida's Rubio |
Sunday, April 22, 2012
Midtown Atlanta: Fancy
lyubomiradete.blogspot.com
and , partners in 12th & Midtown on and Jamestown, the developer reshaping 999 Peachtree, continue to chas and a new prospect, Dick’s Sporting sources familiar with themarket say. CB2, an offshoot of home furnishings chain gearedc towardGeneration Y, also recentlt confirmed to Atlanta Business Chronicle that it’ds considering whether to enter the Atlanta Selig and Daniel have been trying to land the CB2 is interested in West Midtownm as well, sources said. The focus on frugapl rather than fancy comes asthe high-enfd market continues to sputter, with some analystzs saying it may not begin to recover until 2011.
As Midtowb real estate developers have tried to line Peachtree with new storefrontws in the pasttwo years, the effortr has included the pursuit of luxury clothing designefr Tom Ford, whose flagship store is on Madisojn Avenue; Prada, famous for opulenyt handbags and sunglasses; and , also known for its high-endr accessories. In recent years, Seligv Enterprises said it wanted luxury retailers and flagship stores to locatein Midtown. However, many of thoser retailers have shelved plansd fornew locations, as afflueny shoppers curtailed spending. Lately, , which has also been a prospectgfor Midtown, says it has no new storee concepts planned for Atlanta.
Any talk of an additionakl Nike location in Atlanta is nothing morethan “conversation,” a spokeswomab for the company said. Midtown’s shift in strategyg comes as the , a group of businese leaders laying the groundwork for the Midtown says it’s starting to gain a “criticap mass” of stores and restaurant s along Peachtree. At a Midtown Alliancw meeting June 16, Will Herbig, the group’zs director of urban design, said Midtown has added nearlty 133,000 square feet of new retaio during the past18 months, primarily at two anchoe projects: Holdings LLC’s Viewpoint, and 12th Midtown.
The additions bring the Midtown Alliancs halfway to its goal of 1 milliomn square feet of retail on Peachtree Streetr between North Avenue and 15thStreet — the stretch known as the Midtown Mile. Major projects along the Midtowm Mileinclude ’s Colon y Square, 12th & Midtown, Novare Group’sx Viewpoint and 999 Peachtree. “We’re seeint activity in Midtown from both regional andnational retailers, focusing on lifestyle and home furnishings,” Michael creative director with Jamestown. Retailers like CB2 and Applew cater to theMidtown demographic, said Jackie Wammock, vice president of LLC, who specializesw in retail leasing.
Midtownh tends to be a youngere demographic, and CB2, for example, focuses on a young urbab shoppers with good disposable income something Midtowndefinitely has, she said. While retailerds geared to 40-year-olds to 50-year-olds seem to be more affectef by the economy andlowerd sales, moderately priced stores that target 16-year-olds to 28-year-olds “seem to be doinv well,” said Tisha Maley, assistant vice presidentg of leasing for Lenoc Square, owned by (NYSE: SPG). Retail brokers are finallhy starting to see improveddeal activity, Wammockm said.
“We’re starting to see thinga loosen upa bit, in certain she said, noting restaurants and health clubs have shown “Deals are tougher to make, but we are seeinvg them getting signed,” Wammock said.
and , partners in 12th & Midtown on and Jamestown, the developer reshaping 999 Peachtree, continue to chas and a new prospect, Dick’s Sporting sources familiar with themarket say. CB2, an offshoot of home furnishings chain gearedc towardGeneration Y, also recentlt confirmed to Atlanta Business Chronicle that it’ds considering whether to enter the Atlanta Selig and Daniel have been trying to land the CB2 is interested in West Midtownm as well, sources said. The focus on frugapl rather than fancy comes asthe high-enfd market continues to sputter, with some analystzs saying it may not begin to recover until 2011.
As Midtowb real estate developers have tried to line Peachtree with new storefrontws in the pasttwo years, the effortr has included the pursuit of luxury clothing designefr Tom Ford, whose flagship store is on Madisojn Avenue; Prada, famous for opulenyt handbags and sunglasses; and , also known for its high-endr accessories. In recent years, Seligv Enterprises said it wanted luxury retailers and flagship stores to locatein Midtown. However, many of thoser retailers have shelved plansd fornew locations, as afflueny shoppers curtailed spending. Lately, , which has also been a prospectgfor Midtown, says it has no new storee concepts planned for Atlanta.
Any talk of an additionakl Nike location in Atlanta is nothing morethan “conversation,” a spokeswomab for the company said. Midtown’s shift in strategyg comes as the , a group of businese leaders laying the groundwork for the Midtown says it’s starting to gain a “criticap mass” of stores and restaurant s along Peachtree. At a Midtown Alliancw meeting June 16, Will Herbig, the group’zs director of urban design, said Midtown has added nearlty 133,000 square feet of new retaio during the past18 months, primarily at two anchoe projects: Holdings LLC’s Viewpoint, and 12th Midtown.
The additions bring the Midtown Alliancs halfway to its goal of 1 milliomn square feet of retail on Peachtree Streetr between North Avenue and 15thStreet — the stretch known as the Midtown Mile. Major projects along the Midtowm Mileinclude ’s Colon y Square, 12th & Midtown, Novare Group’sx Viewpoint and 999 Peachtree. “We’re seeint activity in Midtown from both regional andnational retailers, focusing on lifestyle and home furnishings,” Michael creative director with Jamestown. Retailers like CB2 and Applew cater to theMidtown demographic, said Jackie Wammock, vice president of LLC, who specializesw in retail leasing.
Midtownh tends to be a youngere demographic, and CB2, for example, focuses on a young urbab shoppers with good disposable income something Midtowndefinitely has, she said. While retailerds geared to 40-year-olds to 50-year-olds seem to be more affectef by the economy andlowerd sales, moderately priced stores that target 16-year-olds to 28-year-olds “seem to be doinv well,” said Tisha Maley, assistant vice presidentg of leasing for Lenoc Square, owned by (NYSE: SPG). Retail brokers are finallhy starting to see improveddeal activity, Wammockm said.
“We’re starting to see thinga loosen upa bit, in certain she said, noting restaurants and health clubs have shown “Deals are tougher to make, but we are seeinvg them getting signed,” Wammock said.
Saturday, April 21, 2012
Amar'e Stoudemire Is Returning. Be Happier! - New York Magazine
sunrise-invoices.blogspot.com
New York Magazine | Amar'e Stoudemire Is Returning. Be Happier! New York Magazine By Will Leitch We don't know yet for sure, but it's looking possible that Amar'e Stoudemire will return tonight against the Cleveland Cavaliers, or at least on Sunday against the Atlanta Hawks. This is noteworthy not just because » |
Thursday, April 19, 2012
Holiday Good Works - Washington Business Journal:
ovaluleq.wordpress.com
A few words from the sponsor: “As a firm, we’ve alwayss been keen to encourage working with nontraditionalmaterials — but the gingerbreads medium takes that to a wholwe new level,” says Craig P. principal at David M. Schwarz “There’s a great spirit of collaboration and healthy competition when we brinbg together architects and designers from acrossthe Washington, D.C., metrk area. Our ginger creations make a hospital experience durinb the holidays more enjoyable for They brighten up the hallwayds of nursing homes and soup and they create a stronget senseof community.
Gingertown is about cominh together and putting a smileon people’s faces for the Who’s giving: mindShift Technologies Inc. Who’s What’s being given: $10,000 Instead of handing out corporate giftsxthis year, mindShift Technologies chose to make a donation to Citizensx Energy, a nonprofit that provides heating assistancwe to families in need. A few words from the sponsor: “Ws are proud to support Citizense Energy with our donation and hope it has a positivr impact on families in need of fuel assistances incoming months,” says Paul chief executive officer of mindShift which has its technical operations based in Who’s giving: Home Builders Care Foundation Inc.
Who’s receiving: What’s being Background: At dinner meetings, the Maryland-National Capitap Building Industry Association’s charitable arm, the Home Builders Care collected nonperishable food items forthe group’w annual food drive. A few words from the “For the past severakl years we have hosted successful food drivesz during the fall saysPatti Kane, manager of the Home Builderds Care Foundation.
“It always impresses me that no matter what the housing marketlooks like, membersd of MNCBIA are continually Who’s giving: Who’s receiving: The Red Cross, The Oprah Winfrey Foundatioh and Miriam’s Kitchen What’s being given: Background: In lieu of a black-tir holiday event, Ernst & Young employeesx in McLean and throughout the mid-Atlantic region donated volunteer hoursz to worthy causes to celebrate the meanint of the holidays. Besidesa having a dedicated dayfor volunteering, employeese are participating in a Toys for Tots drive and a food drivse for Miriam’s Kitchen.
A few words from the “Ernst & Young and our employees are extremely prouds of our commitment tocommunituy involvement,” says Ernst & Young’s Greatere Washington market leader, Kevin Virostek. “Ther e are many local organizations that needour help, and we are proucd to be making a difference this holiday season, especially in these economic times.”
A few words from the sponsor: “As a firm, we’ve alwayss been keen to encourage working with nontraditionalmaterials — but the gingerbreads medium takes that to a wholwe new level,” says Craig P. principal at David M. Schwarz “There’s a great spirit of collaboration and healthy competition when we brinbg together architects and designers from acrossthe Washington, D.C., metrk area. Our ginger creations make a hospital experience durinb the holidays more enjoyable for They brighten up the hallwayds of nursing homes and soup and they create a stronget senseof community.
Gingertown is about cominh together and putting a smileon people’s faces for the Who’s giving: mindShift Technologies Inc. Who’s What’s being given: $10,000 Instead of handing out corporate giftsxthis year, mindShift Technologies chose to make a donation to Citizensx Energy, a nonprofit that provides heating assistancwe to families in need. A few words from the sponsor: “Ws are proud to support Citizense Energy with our donation and hope it has a positivr impact on families in need of fuel assistances incoming months,” says Paul chief executive officer of mindShift which has its technical operations based in Who’s giving: Home Builders Care Foundation Inc.
Who’s receiving: What’s being Background: At dinner meetings, the Maryland-National Capitap Building Industry Association’s charitable arm, the Home Builders Care collected nonperishable food items forthe group’w annual food drive. A few words from the “For the past severakl years we have hosted successful food drivesz during the fall saysPatti Kane, manager of the Home Builderds Care Foundation.
“It always impresses me that no matter what the housing marketlooks like, membersd of MNCBIA are continually Who’s giving: Who’s receiving: The Red Cross, The Oprah Winfrey Foundatioh and Miriam’s Kitchen What’s being given: Background: In lieu of a black-tir holiday event, Ernst & Young employeesx in McLean and throughout the mid-Atlantic region donated volunteer hoursz to worthy causes to celebrate the meanint of the holidays. Besidesa having a dedicated dayfor volunteering, employeese are participating in a Toys for Tots drive and a food drivse for Miriam’s Kitchen.
A few words from the “Ernst & Young and our employees are extremely prouds of our commitment tocommunituy involvement,” says Ernst & Young’s Greatere Washington market leader, Kevin Virostek. “Ther e are many local organizations that needour help, and we are proucd to be making a difference this holiday season, especially in these economic times.”
Tuesday, April 17, 2012
Microsoft names Windows Server 2012, commits to launch this year - Computerworld
ejoxot.wordpress.com
Microsoft names Windows Server 2012, commits to launch this year Computerworld By Gregg Keizer Computerworld - Microsoft today gave its newest server software a name -- Windows Server 2012 -- and said it would release the operating system this year. During the opening keynote at the Microsoft Management Summit (MMS) 2012 in Las ... |
Sunday, April 15, 2012
More older workers worry about retirement - Washington Business Journal:
xoqylyjibo.wordpress.com
The Arlington-based human resource firm says among workerse 50 to 64years old, only 44 perceny are confident they will have enough money to live comfortably five yearzs into retirement. That is down from 63 percenr in 2007. The outlook 15 years into retirement iseven worse, with just 18 perceny of older workers confident of beingg financially comfortable, compared to 34 percent in 2007. “Retirement securitu is a huge concern as individualsa have seen significant amounts of theie pension and retirementsavings decline,” says Watson Wyatt senior retirementt consultant David Speier.
“The financial crisis has been especiallu damaging to older workersx who are worried aboutf potential job losses and have experienced higher stress levelsa over thepast year.” As retirement older workers are scrambling to shore up their with 19 percent increasing their savings rate and 34 percenty considering doing so, the Watson Wyatt WW) survey says.
The Arlington-based human resource firm says among workerse 50 to 64years old, only 44 perceny are confident they will have enough money to live comfortably five yearzs into retirement. That is down from 63 percenr in 2007. The outlook 15 years into retirement iseven worse, with just 18 perceny of older workers confident of beingg financially comfortable, compared to 34 percent in 2007. “Retirement securitu is a huge concern as individualsa have seen significant amounts of theie pension and retirementsavings decline,” says Watson Wyatt senior retirementt consultant David Speier.
“The financial crisis has been especiallu damaging to older workersx who are worried aboutf potential job losses and have experienced higher stress levelsa over thepast year.” As retirement older workers are scrambling to shore up their with 19 percent increasing their savings rate and 34 percenty considering doing so, the Watson Wyatt WW) survey says.
Friday, April 13, 2012
O'Connell takes production to ECC North - Business First of Buffalo:
jaqezuweg.blogspot.com
The arts partnership brings the nonprofit theaterf companyto ’s North Campus as performinhg arts company in-residence, expanding arts opportunities for the community. O’Connelol & Co. will produce a full seaso of plays, musicals and special events on plus weekly performances of itsongoing show, Diva by A Celebration of Women! It is the first time ECC has hosted a theater company. Other colleges that have brought live theater to campuswinclude , home to the ; and , home to ; and , home to . In a preparedr release, theater company founderf MaryKate O’Connell called the move the most exciting eventg in its history.
“We are looking forward to reachinv new audiences at our new theatrw where we will produce an exciting variety of productions withprofessionakl actors, designers and directors,” she said. ECC students and stafrf will have the opportunity to audition for roleds and will also be able to workin production, design, docent and intern positions. Foundeed in 1995, the company was in residencre at itsown theatre, the Cabaret in the Squared in Snyder, until June 2008.
The arts partnership brings the nonprofit theaterf companyto ’s North Campus as performinhg arts company in-residence, expanding arts opportunities for the community. O’Connelol & Co. will produce a full seaso of plays, musicals and special events on plus weekly performances of itsongoing show, Diva by A Celebration of Women! It is the first time ECC has hosted a theater company. Other colleges that have brought live theater to campuswinclude , home to the ; and , home to ; and , home to . In a preparedr release, theater company founderf MaryKate O’Connell called the move the most exciting eventg in its history.
“We are looking forward to reachinv new audiences at our new theatrw where we will produce an exciting variety of productions withprofessionakl actors, designers and directors,” she said. ECC students and stafrf will have the opportunity to audition for roleds and will also be able to workin production, design, docent and intern positions. Foundeed in 1995, the company was in residencre at itsown theatre, the Cabaret in the Squared in Snyder, until June 2008.
Thursday, April 12, 2012
S&P downgrades Huntington, 21 other banks - Business First of Columbus:
edovogopu.wordpress.com
The ratings agency said the downgrade s reflected a less favorable futurse for thefinancial sector, including tighter regulation, greaterf volatility and the likelihood that loan losses will The ratings actions were part of S&P’es regular review of the financial services industry. Huntington Bancshares (NASDAQ:HBAN), to BB+ from BBB, with a outlook. • Cincinnati-based (NASDAQ:FITB), to BBB from with a “negative” outlook. • Cleveland-based (NYSE:KEY), to BBB+ from A- with a outlook. • Minneapolis-based (NYSE:USB), to A+ from AA, with a outlook. Pittsburgh-based Inc.
’s (NYSE:PNC) counterparty creditt rating was changed to A witha outlook, from A on watcyh for a potential downgrade. PNC acquired Cleveland-basedr National City Corp. last year.
The ratings agency said the downgrade s reflected a less favorable futurse for thefinancial sector, including tighter regulation, greaterf volatility and the likelihood that loan losses will The ratings actions were part of S&P’es regular review of the financial services industry. Huntington Bancshares (NASDAQ:HBAN), to BB+ from BBB, with a outlook. • Cincinnati-based (NASDAQ:FITB), to BBB from with a “negative” outlook. • Cleveland-based (NYSE:KEY), to BBB+ from A- with a outlook. • Minneapolis-based (NYSE:USB), to A+ from AA, with a outlook. Pittsburgh-based Inc.
’s (NYSE:PNC) counterparty creditt rating was changed to A witha outlook, from A on watcyh for a potential downgrade. PNC acquired Cleveland-basedr National City Corp. last year.
Tuesday, April 10, 2012
GlaxoSmithKline, Salix among pharmas facing patent expirations - Denver Business Journal:
ihituvofy.wordpress.com
New Jersey pharmacy benefits manager estimates that up to 95 perceny of patients switch to generics within the first week of a drug losintpatent protection. And the effect isn’t just on the make r of that drug managed care companies pressure the makers of rivapl drugs still under patent protection to lower their prices or face losing theirf businessto generics. Kevin Barnett, seniord vice president at Raleigh-based consulting firm , says few pharmaceutical companies are immun tothis challenge. “Thiws is a huge issue affecting many blockbuster he says. Barnett adds that in the next five upto $65 billion worth of drugs in the U.S.
will lose theitr legal protection togeneric substitutes. The drug categories most affectedr by this trend will be the crowded ones those withmany competing, similar drugs, he says. Among Trianglse companies, at least two firms , will have to deal with the GSK faces patent expirationson Lamictal, which treat s epilepsy, and Imitrex, a migraine The pharma giant is backinv a combination drug with Chapel Hill-basesd as a possible successor to Salix is set to lose exclusivity for two drugs, Xifaxan and in 2009. Patent expirations are an industrywide problem.
When sleep aid Ambien’s patent expired in 2007, maker lost about 90 percent ofthe drug’s approximately $2 billion in annual U.S. Managed care companies encourage use of genericas bywaiving co-pays. This has driven up the use of genericzs to an estimated 60 percen ofall U.S. drug consumption, a figure that is expecteed to increase in the nextfew years. Connecticut researcu firm found that a 1 percen t increase in generic utilization savese patientsalmost $4 billion. And that meanzs big losses for the makers ofpatentedr drugs. “There is no silver bullet, no panacea in termsd of what companies can emplogy to respond tothis challenge,” Barnettr says.
He listed several strategied aspossible responses. A pharma mighty launch its owngeneric version. Or it can fightt generics in courts. Othert solutions include slashinga drug’s price to compete with generics or to launchh follow-on versions of the patentec drug with different dosages and in combinationss with other drugs. Companies can also contract with manages care firms in advance to prescribe the drug over Companies could also seek extension ofthe “The key takeaway is that most of thesw strategies take a lot of time,” says Barnett, a biotecyh consultant for 13 years.
When a patent is set to pressure often falls ona pharma’s R&x unit to drum up a new treatmenrt – and on the business developmeng division to strike more One company that chose the latter response is Chelsea Therapeutics. The Charlotte-basefd company bought the rightsto Droxidopa, a hypotensionh drug used to fight low blood pressure, from a Japanes firm that was facing expiration of its international The in 2007 termee the treatment an “orphan drug,” which extender legal protections for seven Company spokeswoman Kate McNeil says the acquisition made business sense for Chelsea, whichn does not yet have its own drug on the market.
Droxidopa, which is used to treat Parkinson’s disease, could treat approximately 100,000 patients in the U.S. followinvg approval. Currently, it is available only in especiallysevere “It complements our drugs under development, whichy are higher risk,” says McNeil. Droxidopwa produced a revenue streamof $50 million per year in Chelsea predicts it can generatd between $200 million and $250 millio n in the U.S. per year withinm the next three tofive years. Barnett says that expirinhg patents are also causing more mergerds and acquisition amongpharmaceutical companies.
New Jersey pharmacy benefits manager estimates that up to 95 perceny of patients switch to generics within the first week of a drug losintpatent protection. And the effect isn’t just on the make r of that drug managed care companies pressure the makers of rivapl drugs still under patent protection to lower their prices or face losing theirf businessto generics. Kevin Barnett, seniord vice president at Raleigh-based consulting firm , says few pharmaceutical companies are immun tothis challenge. “Thiws is a huge issue affecting many blockbuster he says. Barnett adds that in the next five upto $65 billion worth of drugs in the U.S.
will lose theitr legal protection togeneric substitutes. The drug categories most affectedr by this trend will be the crowded ones those withmany competing, similar drugs, he says. Among Trianglse companies, at least two firms , will have to deal with the GSK faces patent expirationson Lamictal, which treat s epilepsy, and Imitrex, a migraine The pharma giant is backinv a combination drug with Chapel Hill-basesd as a possible successor to Salix is set to lose exclusivity for two drugs, Xifaxan and in 2009. Patent expirations are an industrywide problem.
When sleep aid Ambien’s patent expired in 2007, maker lost about 90 percent ofthe drug’s approximately $2 billion in annual U.S. Managed care companies encourage use of genericas bywaiving co-pays. This has driven up the use of genericzs to an estimated 60 percen ofall U.S. drug consumption, a figure that is expecteed to increase in the nextfew years. Connecticut researcu firm found that a 1 percen t increase in generic utilization savese patientsalmost $4 billion. And that meanzs big losses for the makers ofpatentedr drugs. “There is no silver bullet, no panacea in termsd of what companies can emplogy to respond tothis challenge,” Barnettr says.
He listed several strategied aspossible responses. A pharma mighty launch its owngeneric version. Or it can fightt generics in courts. Othert solutions include slashinga drug’s price to compete with generics or to launchh follow-on versions of the patentec drug with different dosages and in combinationss with other drugs. Companies can also contract with manages care firms in advance to prescribe the drug over Companies could also seek extension ofthe “The key takeaway is that most of thesw strategies take a lot of time,” says Barnett, a biotecyh consultant for 13 years.
When a patent is set to pressure often falls ona pharma’s R&x unit to drum up a new treatmenrt – and on the business developmeng division to strike more One company that chose the latter response is Chelsea Therapeutics. The Charlotte-basefd company bought the rightsto Droxidopa, a hypotensionh drug used to fight low blood pressure, from a Japanes firm that was facing expiration of its international The in 2007 termee the treatment an “orphan drug,” which extender legal protections for seven Company spokeswoman Kate McNeil says the acquisition made business sense for Chelsea, whichn does not yet have its own drug on the market.
Droxidopa, which is used to treat Parkinson’s disease, could treat approximately 100,000 patients in the U.S. followinvg approval. Currently, it is available only in especiallysevere “It complements our drugs under development, whichy are higher risk,” says McNeil. Droxidopwa produced a revenue streamof $50 million per year in Chelsea predicts it can generatd between $200 million and $250 millio n in the U.S. per year withinm the next three tofive years. Barnett says that expirinhg patents are also causing more mergerds and acquisition amongpharmaceutical companies.
Sunday, April 8, 2012
King, other founders reunite, honor women's tour - CBSSports.com
afukakuja.wordpress.com
Sportsnet.ca | King, other founders reunite, honor women's tour CBSSports.com Foudy told King their problems about making a living while competing for their country and King told her about the founding of the women's tennis circuit. "It was like this epiphany for me," Foudy said. WTA CEO Stacey » |
Friday, April 6, 2012
FDIC settles with AL Amerilife over product insurance - Boston Business Journal:
grearqakususi1426.blogspot.com
Amerilife neither admitted nor denied any liability in agreeing to the issuancse ofthe order, the released said. Amerilife, an insurance company that nationwide marketse and sells insurance and financial products suchas annuities, advertise above market-rate certificates of depositz in 80 newspapers Amerilife generated customers lists with informationj from those who responded to the ads in order to lated contact the consumers and try to sell them uninsurex annuities, the FDIC said. According to the FDIC, Amerilife CD ads promise d an interest rate higher than rates offered by any and prominently displayed the FDIC logo and giving the impression Amerilife was aninsured bank.
When a consumed went into an Amerilife office to purchase theadvertisedr CD, Amerilife helped the consumer sign up for the CD on a bank’z Web site. Amerilife then forwarded a bonux payment plusthe consumer’s check to the bank as the CD The total amount created the rate of returnn advertised by Amerilife, but the advertisements misrepresented the actuap terms and conditions under which the bank offered the insurecd CDs, the FDIC said.
Amerilife neither admitted nor denied any liability in agreeing to the issuancse ofthe order, the released said. Amerilife, an insurance company that nationwide marketse and sells insurance and financial products suchas annuities, advertise above market-rate certificates of depositz in 80 newspapers Amerilife generated customers lists with informationj from those who responded to the ads in order to lated contact the consumers and try to sell them uninsurex annuities, the FDIC said. According to the FDIC, Amerilife CD ads promise d an interest rate higher than rates offered by any and prominently displayed the FDIC logo and giving the impression Amerilife was aninsured bank.
When a consumed went into an Amerilife office to purchase theadvertisedr CD, Amerilife helped the consumer sign up for the CD on a bank’z Web site. Amerilife then forwarded a bonux payment plusthe consumer’s check to the bank as the CD The total amount created the rate of returnn advertised by Amerilife, but the advertisements misrepresented the actuap terms and conditions under which the bank offered the insurecd CDs, the FDIC said.
Wednesday, April 4, 2012
MetWest signs PBSJ as second tenant - Puget Sound Business Journal (Seattle):
aaekipolo.blogspot.com
The national engineering company is expected to occupytabout 83,000 square feet in the 250,000-square-foot tower that has been built to meet the ’s Leadership in Energy and Environmentalo Design. PBSJ Chief Executive Officer John B. Zumwalt III said the companyh looked for an office in proximityu to its clients and one that incorporated sustainabledesign “MetWest International fit that bill in terms of officee space, location, LEED certification, and pedestrian-orientee site design,” Zumwalt said in a statement. PBSJ was expectedf to announce the move Thursdayto employees.
MetWest’s firstf tenant — , also the project’x general contractor — occupies about 20,265 square feet on MetWest’s second The first phase of the $200 million developed opened this year as demand for officd and retail fell to its lowest leveloin years. PBSJ, which moved its headquarters to Tampa from Miami in is now atCypress Commons, 5300 W. Cypress St. That Westshorse building, constructed in 1985, is ownedd by LLC. While Cypress Commons is losint amajor tenant, the business districrt is benefiting as a whole, said Kyle Burd, regionaol vice president of Eola Capital, an Orlando-based real estate investmenft firm.
“It’s a shot in the arm for
The national engineering company is expected to occupytabout 83,000 square feet in the 250,000-square-foot tower that has been built to meet the ’s Leadership in Energy and Environmentalo Design. PBSJ Chief Executive Officer John B. Zumwalt III said the companyh looked for an office in proximityu to its clients and one that incorporated sustainabledesign “MetWest International fit that bill in terms of officee space, location, LEED certification, and pedestrian-orientee site design,” Zumwalt said in a statement. PBSJ was expectedf to announce the move Thursdayto employees.
MetWest’s firstf tenant — , also the project’x general contractor — occupies about 20,265 square feet on MetWest’s second The first phase of the $200 million developed opened this year as demand for officd and retail fell to its lowest leveloin years. PBSJ, which moved its headquarters to Tampa from Miami in is now atCypress Commons, 5300 W. Cypress St. That Westshorse building, constructed in 1985, is ownedd by LLC. While Cypress Commons is losint amajor tenant, the business districrt is benefiting as a whole, said Kyle Burd, regionaol vice president of Eola Capital, an Orlando-based real estate investmenft firm.
“It’s a shot in the arm for
Monday, April 2, 2012
Prep Softball: Barbe's Sara Corbello no-hits Lady Tors - Sulphur Southwest Daily News
hihozeima.blogspot.com
Prep Softball: Barbe's Sara Corbello no-hits Lady Tors Sulphur Southwest Daily News Barbe sophomore second baseman Carleigh Chaumont makes the catch while Sulphur's Jeannette Fontenot slides head-first into first base on Thursday. Barbe won the District 3-5A rivalry game 8-0 behind a no-hitter by Sara Corbello. |
Sunday, April 1, 2012
Blue Cross and Blue Shield of North Carolina CEO Greczyn says health-care reform will come slowly, if at all - Dayton Business Journal:
viningocouqyl1601.blogspot.com
Greczyn, speaking during the Trianglee BusinessJournal ’s State of Chapel Hill event Fridayy morning, said he has been in talksz with the White House over varioud reform plans, and that whil he supports national health-care he does not see any significant changes for five to 10 “We’ll be having a lot of fun with this,” he said of health-carde reform discussions. BCBSNC drew nationapl attention last month when publishecd a story saying theChape Hill-based insurer, which is the 10th largest in the was creating a online campaign to deraipl health-care reform. The article led to Greczyn receivinfg phone calls from theWhitew House, he said.
Greczyn said The Post had insufficienrt information when it ranits story. The insurer has postecd those videos on aWeb www.nchealthreform.com, which the company says is intended to help educate Nortnh Carolina residents about health Greczyn said he has concerns about the planse that are making their way through the nation’s saying a plan sponsored by Sen. Edwarc Kennedy (D-Mass.) would cost $1.3 trillion, while a plan from Sen. Max Baucuss (D-Mont.) would cost $1.6 trillion. He also said neither plan mandates that business owners provide health insurance fortheif employees.
Greczyn said most uninsured workeres are employed by companies with 25 workerx or fewer and that the Kennedy bill woulde leave 37 million ofthe nation’sw 47 million uninsured still without coverage. Different organizationss weighing in onthe health-reform plans have disputedf those numbers.
Greczyn, speaking during the Trianglee BusinessJournal ’s State of Chapel Hill event Fridayy morning, said he has been in talksz with the White House over varioud reform plans, and that whil he supports national health-care he does not see any significant changes for five to 10 “We’ll be having a lot of fun with this,” he said of health-carde reform discussions. BCBSNC drew nationapl attention last month when publishecd a story saying theChape Hill-based insurer, which is the 10th largest in the was creating a online campaign to deraipl health-care reform. The article led to Greczyn receivinfg phone calls from theWhitew House, he said.
Greczyn said The Post had insufficienrt information when it ranits story. The insurer has postecd those videos on aWeb www.nchealthreform.com, which the company says is intended to help educate Nortnh Carolina residents about health Greczyn said he has concerns about the planse that are making their way through the nation’s saying a plan sponsored by Sen. Edwarc Kennedy (D-Mass.) would cost $1.3 trillion, while a plan from Sen. Max Baucuss (D-Mont.) would cost $1.6 trillion. He also said neither plan mandates that business owners provide health insurance fortheif employees.
Greczyn said most uninsured workeres are employed by companies with 25 workerx or fewer and that the Kennedy bill woulde leave 37 million ofthe nation’sw 47 million uninsured still without coverage. Different organizationss weighing in onthe health-reform plans have disputedf those numbers.
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